Search on: 7-ETHOXYCOUMARIN O-DEALKYLASE 
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Descriptor English:   7-Alkoxycoumarin O-Dealkylase 
Descriptor Spanish:   7-Alcoxicumarina O-Dealquilasa 
Descriptor Portuguese:   O-Dealquilase 7-Alcoxicumarina 
Synonyms English:   7-Ethoxycoumarin O-Dealkylase
7-Ethoxycoumarin O-Deethylase  
Tree Number:   D08.811.682.690.708.170.040.024
Definition English:   A drug-metabolizing enzyme found in the hepatic, placental and intestinal microsomes that metabolizes 7-alkoxycoumarin to 7-hydroxycoumarin. The enzyme is cytochrome P-450- dependent. 
History Note English:   90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   24513 
Unique Identifier:   D015660 

Occurrence in VHL:
 

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